Domiphen bromide is a cationic active quaternary ammonium salt and also an inhibitor of HERG channels ( IC 50 : 9 nM), aminopeptidase-like enzymes , Escherichia coli alkaline phosphatase , and α-chymotrypsin . Domiphen bromide has multiple activities such as antibacterial , antimalarial, and disinfectant properties, and it is also a synergist of Colistin ( HY-113678 ). Domiphen bromide can be used as a chemical preservative and a cationic surfactant, and it can also be used in the research of bacterial infectious diseases such as pharyngitis, thrush, and oral ulcers.
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