L-DICENTRINE

L-DICENTRINE
  • CAS No.:28832-07-7
Other grades of this product :
L-DICENTRINE Basic information
Product Name:L-DICENTRINE
Synonyms:(7aR)-6,7,7a,8-Tetrahydro-10,11-dimethoxy-7-methyl-5H-benzo[g]-1,3-benzodioxolo[6,5,4-de]quinoline;Cepharanthine α-base;Eximine;10,11-Dimethoxy-7-methyl-6,7,7A,8-tetrahydro-5H-benzo[G][1,3]benzodioxolo[6,5,4-de]quinoline;5H-Benzo[G]-1,3-benzodioxolo[6,5,4-de]quinoline, 6,7,7A,8-tetrahydro-10,11-dimethoxy-7-methyl-;Inchi=1/C20H21no4/C1-21-5-4-11-7-17-20(25-10-24-17)19-13-9-16(23-3)15(22-2)8-12(13)6-14(21)18(11)19/H7-9,14H,4-6,10H2,1-3h;(R)-(-)-DICENTRINE;L-DICENTRINE
CAS:28832-07-7
MF:C20H21NO4
MW:339.39
EINECS:
Product Categories:Heterocycles;Aromatics;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:28832-07-7.mol
L-DICENTRINE Chemical Properties
Boiling point 480.7±45.0 °C(Predicted)
density 1.266±0.06 g/cm3 (20 ºC 760 Torr)
pka6.65±0.20(Predicted)
Safety Information
MSDS Information
L-DICENTRINE Usage And Synthesis
UsesA natural vascular alpha 1-adrenoceptor antagonist but less prevalent than the D-isomer. It markedly inhibits the contraction of rat stomach muscle strips induced by 5-HT, histamine, K+ and Ca2+ after high K+ depolarization, showing a non-competitive antagonism and could be a potential muscle relaxant. Studies suggest that it has protective effect of on acute myocardial Iichemia and anoxia lesion.
L-DICENTRINE Preparation Products And Raw materials

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