POPSO is a zwitterionic buffer , increases osmolality and shows marked inhibition of anion uniport. POPSO inhibits chloride uniport with an IC 50 value of 24 mM. POPSO enhances copper uptake and toxicity in alga, impairs mitochondrial inner membrane. The working pH range of POPSO sesquisodium salt is 7.2-8.5.
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