Sudan IV

Overview

Sudan IV is an agonist of the aryl hydrocarbon receptor ( AhR ) that activates downstream signaling pathways and induces CYP1A1 expression. Sudan IV promotes CYP1A1 gene transcription by activating AhR-ARNT heterodimers and binding to exogenous response elements (XREs) on DNA, thereby enhancing drug metabolizing enzyme activity. Sudan IV can be used to study the toxicity mechanisms of industrial dyes and the effects of interactions with serum proteins (such as bovine serum albumin (BSA)) on their distribution in vivo. Sudan IV is a fat-soluble diazo dye that can be used to stain lipids, triglycerides, and lipoproteins on frozen sections.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Environmental Pollutants | Products > Signaling Pathways > Aryl Hydrocarbon Receptor | Products > Signaling Pathways > Cytochrome P450 | Products > Signaling Pathways > Biochemical Assay Reagents

Product Information

• Catalog No.: HY-D0932
• CAS No.: 85-83-6
• Molecular Formula: C24H20N4O
• Molecular Weight: 380.44
• Purity: 98.0%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source