HUMULONE

HUMULONE
  • CAS No.:26472-41-3
Other grades of this product :
HUMULONE Basic information
Product Name:HUMULONE
Synonyms:(6S)-3,5,6-trihydroxy-2-(3-methylbutanoyl)-4,6-bis(3-methylbut-2-enyl)cyclohexa-2,4-dien-1-one;(6R)-3,5,6-trihydroxy-2-isovaleryl-4,6-bis(3-methylbut-2-enyl)cyclohexa-2,4-dienone;α-bitter acid;Humulone, mixture of homologues;α-Bitter acid, α-Lupulic acid;(6R)-2-(3-Methylbutyryl)-3,5,6-trihydroxy-4,6-bis(3-methyl-2-butenyl)-2,4-cyclohexadiene-1-one;(6R)-4,6-Diprenyl-3,5,6-trihydroxy-2-(1-oxo-3-methylbutyl)-2,4-cyclohexadiene-1-one;[R,(-)]-3,5,6-Trihydroxy-4,6-bis(3-methyl-2-butenyl)-2-(3-methyl-1-oxobutyl)-2,4-cyclohexadien-1-one
CAS:26472-41-3
MF:C21H30O5
MW:362.46
EINECS:247-725-0
Product Categories:Miscellaneous Natural Products
Mol File:26472-41-3.mol
HUMULONE Chemical Properties
Melting point 65-66.5℃
alpha D20 -212° (1.0 g in 15.5 g 96% alc)
Boiling point 414.06°C (rough estimate)
density 1.157±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 1.6120 (estimate)
storage temp. −20°C
pka4.50±1.00(Predicted)
Safety Information
WGK Germany 3
10-23
MSDS Information
HUMULONE Usage And Synthesis
Uses(R)-Humulone (CAS# 26471-41-3) can be used as a chemosensory receptor ligand.
Purification MethodsCrystallise humulon from Et2O. It dissolves slightly in hot H2O but precipitates on cooling. It has max () 237 (13,760) and 282 (8,330) in EtOH. [Wollmer Chem Ber 49 780 1916, Carson J Am Chem Soc 73 4652 1951, Beilstein 8 II 537, 8 III 4034, 8 IV 3410.]
HUMULONE Preparation Products And Raw materials
Raw materials1-Butanone, 3-methyl-1-[2,4,6-trihydroxy-3,5-bis(3-methyl-2-buten-1-yl)phenyl]-

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