TAMRA DBCO, 5-isomer is a derivative of TAMRA fluorescent isomer with a DBCO functional group. TAMRA DBCO, 5-isomer undergoes strain-promoted azide-alkyne cycloaddition (SPAAC) under copper-free catalytic conditions. TAMRA DBCO, 5-isomer serves as a FRET acceptor for FAM fluorophores. TAMRA DBCO, 5-isomer can label proteins, peptides, nucleic acids and all azide-modified biomolecules, and is suitable for fluorescence imaging and flow cytometry to quantify intracellular SPAAC reactions.
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