Omeprazole sulfide (Ufiprazole) is a metabolic degradation product of Omeprazole ( HY-B0113 ). Omeprazole sulfide acts as a modulator of AhR . Omeprazole sulfide in cells with low CYP3A4 expression, functions as an AhR antagonist; however, in cells with high CYP3A4 expression, it is rapidly metabolized to Omeprazole , thereby acting as an AhR agonist. Omeprazole sulfide exhibits antibacterial activity when conjugated with silver nanoparticles (AgNPs). Omeprazole sulfide can be used in research on acid suppression and bacterial infections.
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