D-Isoleucine

D-Isoleucine
  • CAS No.:319-78-8
  • Grade:99.83%
  • Formula:C6H13NO2
  • M.W.:131.18

Overview

D-Isoleucine is a selective competitive activator of the Asc-1 antiporter (Ki=0.98 mM). D-Isoleucine promotes the release of D-serine and glycine by binding to the Asc-1 protein on the neuronal cell membrane, and enhances NMDA receptor-dependent synaptic plasticity. D-Isoleucine can be used in the study of neurodegenerative diseases (such as Alzheimer's disease and schizophrenia). D-Isoleucine also acts as a non-classical D-amino acid, interferes with bacterial peptidoglycan synthesis, and inhibits the formation of Staphylococcus aureus biofilm, and has potential antibacterial application value[1][2].

Application

Products | Products > Disease Areas > Infection | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Bacterial Infection | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > ASCT

Product Information

  • Catalog No.: HY-I1070
  • CAS No.: 319-78-8
  • Molecular Formula: C6H13NO2
  • Molecular Weight: 131.18
  • Purity: 99.83%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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