2'-Acetylacteoside (Standard) is the analytical standard of 2'-Acetylacteoside (2'-AA) ( HY-N0026 ). This product is intended for research and analytical applications. 2'-Acetylacteoside is a natural compound with oral activity and blood-brain barrier permeability. 2'-Acetylacteoside exhibits MAO‑B inhibitory activity ( IC 50 = 17.71 μM, K i = 13.81 μM). 2'-Acetylacteoside downregulates the expression of RANK , TRAF6 , NF‑κB , NFATc1 and IKKβ , disrupts the RANKL/RANK interaction, blocks downstream signaling pathways, and increases the level of phosphorylated Akt . 2'-Acetylacteoside possesses potent anti-osteoclastogenic, anti-bone resorptive, pro-neurogenic, neuroprotective and antioxidant activities. 2'-Acetylacteoside can be used in the research of osteoporosis, ischemic stroke and Parkinson's disease.
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