Other grades of this product :
| JTC 801 Basic information |
| Product Name: | JTC 801 | | Synonyms: | JTC 801;N-(4-Amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]benzamidehydrochloride;N-(4-Amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]benzamide monohydrochloride;JTC 801 HCl;JTC-801 hydrochloride;JTC-801/JTC801;N-(4-AMino-2-Methyl-quinolin-6-yl)-2-(4-ethyl-phenoxyMethyl)-benzaMide hydrochloride;Benzamide,N-(4-amino-2-methyl-6-quinolinyl)-2-[(4-ethylphenoxy)methyl]-, hydrochloride | | CAS: | 244218-51-7 | | MF: | C26H25N3O2.ClH | | MW: | 447.963 | | EINECS: | | Product Categories: | Inhibitors | | Mol File: | 244218-51-7.mol |
| JTC 801 Chemical Properties |
| Melting point | 235℃ | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO: ≥20mg/mL | | form | powder | | color | tan | | InChIKey | NQLIYKXNAXKMBL-UHFFFAOYSA-N |
| Hazard Codes | Xi | | Risk Statements | 36 | | Safety Statements | 26 | | WGK Germany | 1 |
| JTC 801 Usage And Synthesis |
| Uses | JTC 801 is a novel opioid receptor-like1 (ORL1) receptor antagonist. | | Biological Activity | High affinity, selective NOP receptor antagonist (K i = 8.2 nM). Displays approximately 12.5-, 129- and 1055-fold selectivity over human μ -, κ - and δ -opioid receptors respectively. In vivo shows anti-nociceptive effects in acute pain models. Orally active. |
| JTC 801 Preparation Products And Raw materials |
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