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| N-(1-oxohexyl)-glycine Basic information |
| N-(1-oxohexyl)-glycine Chemical Properties |
| Melting point | 90-92°C | | Boiling point | 387.2±25.0 °C(Predicted) | | density | 1.074±0.06 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 3.60±0.10(Predicted) | | color | White to Off-White |
| N-(1-oxohexyl)-glycine Usage And Synthesis |
| Description | Hexanoyl glycine is an acylated amino acid that is used as a urinary biomarker for several indications. It is normally biosynthesized from hexanoyl-CoA and glycine by the mitochondrial enzyme glycine N-acyltransferase. Increased urinary excretion of hexanoyl glycine in humans is indicative of a deficiency in medium-chain acyl-CoA dehydrogenase. Increased urinary hexanoyl glycine can also be used as a biomarker for exposure to gamma radiation. Levels of hexanyl glycine can also be elevated during cancer, while they are decreased 20-fold in mice following treatment with the PPARα ligand Wy 14643. | | Chemical Properties | White Solid | | Uses | An acylaminoacid derivative as antipsychotic drug | | Uses | An acylaminoacid derivative as antipsychotic drug. | | Definition | ChEBI: An N-acylglycine in which the acyl group is specified as hexanoyl. |
| N-(1-oxohexyl)-glycine Preparation Products And Raw materials |
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