Rubiadin is an orally active free radical scavenger that inhibits the activation of the NF-κB pathway. Rubiadin inhibits osteoclast formation, bone resorption, lipid peroxidation, HBV DNA replication and cancer cell proliferation; reduces pro-inflammatory cytokine levels; induces cancer cell apoptosis ; and possesses antifungal , antimalarial, antibacterial and anticonvulsant activities. Rubiadin can be used in the research of osteoporosis, acute inflammation, chronic inflammation, carbon tetrachloride-induced liver injury, Alzheimer's disease, breast cancer , iron overload disorders, hepatitis B virus infection , colon cancer , liver cancer , T-lymphocytic leukemia, cervical cancer , diabetic nephropathy, epileptic seizures, fungal infections, malaria and bacterial infections .
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