Progoitrin

Overview

Progoitrin is a sulfur-containing glucosinolate, as well as a naturally occurring orally active thioglycoside. Progoitrin acts as a hepatotoxin and antithyroid agent. Progoitrin is quantitatively converted to goitrin in vivo, including via a gastrointestinal hydrolysis pathway that does not require exogenous myrosinase, thereby blocking the organification of iodine in the thyroid gland and inhibiting the uptake and accumulation of radioactive iodine. Progoitrin can be used in studies related to Graves' disease.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Thyroid Disease | Products > Signaling Pathways > Others | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Drug Derivative

Product Information

• Catalog No.: HY-N10348
• CAS No.: 585-95-5
• Molecular Formula: C11H19NO10S2
• Molecular Weight: 389.40
• Purity: 99.98%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 1 mg/mL (2.57 mM); Clear solution
• Availability: In-stock

Source

Original product source