2-MERCAPTO-L-HISTIDINE

2-MERCAPTO-L-HISTIDINE
  • CAS No.:2002-22-4

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.
Other grades of this product :
2-MERCAPTO-L-HISTIDINE Basic information
Product Name:2-MERCAPTO-L-HISTIDINE
Synonyms:L-THIOHISTIDINE;H-HIS(2-MERCAPTO)-OH;H-2-MERCAPTO-HIS-OH;1H-IMIDAZOLE-4-PROPANOIC ACID;2-MERCAPTO-HISTIDINE;2-MERCAPTO-L-HISTIDINE;2-THIOLHISTIDINE;(S)-alpha-amino-2,3-dihydro-2-thioxo-1H-imidazole-4-propionic acid
CAS:2002-22-4
MF:C6H9N3O2S
MW:187.22
EINECS:217-899-2
Product Categories:Heterocycles;Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;Sulfur & Selenium Compounds
Mol File:2002-22-4.mol
2-MERCAPTO-L-HISTIDINE Chemical Properties
Melting point 320-325°C
Boiling point 376.3±52.0 °C(Predicted)
density 1.52±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility Aqueous Acid (Slightly)
form Solid
pkapK1:1.84(+1);pK2:8.47(0);pK3:11.4(SH) (25°C)
color Off-White
Safety Information
MSDS Information
2-MERCAPTO-L-HISTIDINE Usage And Synthesis
Chemical PropertiesColourless Crystals
UsesAn intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blo od cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake.
UsesAn intermediate in the formation of L-egothioneine, a natural amino acid ubiquitously present in cells and tissues of most plants and mammalian species. In humans, L-ergothioneine is found in red blood cells, liver, kidney, brain, seminal fluid, and cataract-free lenses at concentrations ranging from 100 uM to 2 mM. L-ergothioneine is exclusively biosynthesized in fungi and mycobacteria. Hence, humans assimilate it through dietary intake.L-ergothioneine has been proven to act as an antioxidant in vivo and to afford protection from g and UV radiation as well as from singlet oxygen in vivo. Recently, it has been shown that L-ergothioneine protects isolated perfused heart against the deleterious effect of post-ischemic reperfusion.The intermediate, 2-mercaptohistine has been used for the
2-MERCAPTO-L-HISTIDINE Preparation Products And Raw materials
Preparation ProductsL-Histidine

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