4-Fluoro-D-phenylalanine

4-Fluoro-D-phenylalanine
  • CAS No.:18125-46-7
Other grades of this product :
4-Fluoro-D-phenylalanine Basic information
Product Name:4-Fluoro-D-phenylalanine
Synonyms:D-4-FLUOROPHE;D-4-FLUOROPHENYLALANINE;H-D-PHE(P-F)-OH;H-D-PHE(4-F)-OH;H-P-FLUORO-D-PHE-OH;4-FLUORO-D-PHENYLALANINE;P-FLUORO-D-PHENYLALANINE;(R)-2-AMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID
CAS:18125-46-7
MF:C9H10FNO2
MW:183.18
EINECS:
Product Categories:Phenylalanine analogs and other aromatic alpha amino acids;Peptide;Amino Acids;a-amino
Mol File:18125-46-7.mol
4-Fluoro-D-phenylalanine Chemical Properties
Melting point ~245 °C (dec.)
Boiling point 313.3±32.0 °C(Predicted)
density 1.1939 (estimate)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka2.20±0.10(Predicted)
form powder to crystal
color White to Almost white
optical activity[α]20/D +23±2°, c = 1% in H2O
BRN 2416149
CAS DataBase Reference18125-46-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
WGK Germany 3
Hazard Note Harmful
HS Code 29224999
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
4-Fluoro-D-phenylalanine Usage And Synthesis
Chemical PropertiesWhite to off-white powder
Uses4-Fluoro-D-phenylalanine is a building block used in the preparation of new peptidomimetics.
Purification MethodsIt is recrystallised from aqueous EtOH. The (R)-N-acetyl derivative has m 142-145o, [] D -38.6o (c 8, EtOH). [Bennett & Nieman J Am Chem Soc 72 1800 1950, Beilstein 14 III 1268.]
4-Fluoro-D-phenylalanine Preparation Products And Raw materials
Raw materials(R)-3-AMINO-3-(4-FLUORO-PHENYL)-PROPIONIC ACID-->DL-3-(4-Fluorophenyl)alanine
Preparation ProductsL-4-Fluorophenylalanine-->2-(4-FLUOROBENZOYL)ACETIC ACID-->Benzophenone

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