Pronqodine A is an Indoleamine 2,3-Dioxygenase ( IDO ) inhibitor, with an IC 50 of 131.5 nM. Pronqodine A inhibits bradykinin-induced release of PGE2 , 6-keto-prostaglandin F 1α , PGD2 and induces the production of reactive oxygen species ( ROS ) in human synovial sarcoma SW982 cells. Pronqodine A is a good substrate for human quinone reductase NQO1. Pronqodine A can be used for the study of inflammation.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Indoleamine 2,3-Dioxygenase (IDO) | Products > Signaling Pathways > Quinone Reductase | Products > Signaling Pathways > Reactive Oxygen Species (ROS)
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