Mazethramycin B (Compound II) is an antitumor antibiotic . Mazethramycin B can be isolated from the Streptomyces thioluteusM ME561-L4. Mazethramycin B has a broad-spectrum antimicrobial activity (such as MIC s of 1.56 and 6.25 μg/mL for the bacteria Bacillus subtilis PCI 219 and the fungus Candida pseudotropicalis , resepectively). Mazethramycin B significantly increases survival in L1210 leukemia mice model.
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