14-epi-Berkeleylactone F (Compound 8) is a C-14 epimer of Berkeleylactone F ( HY-N8386 ). 14-epi-Berkeleylactone F can be isolated from Penicillium turbatum NRRL 5630. 14-epi-Berkeleylactone F has no significant biological activity against bacterium ( Staphylococcus aureus , Bacillus subtilis and E. coli ), fungi Candida albicans , the parasite Giardia duodenalis and NS-1 murine myeloma cells.
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