5-FLUORO-DL-TRYPTOPHAN

5-FLUORO-DL-TRYPTOPHAN
  • CAS No.:154-08-5
Other grades of this product :
5-FLUORO-DL-TRYPTOPHAN Basic information
Product Name:5-FLUORO-DL-TRYPTOPHAN
Synonyms:.;5-fluorotryptophan;5-Fluoro-DL-tryptophan, 99+%;H-DL-TRP(5-F)-OH;H-5-FLUORO-DL-TRP-OH;DL-5-FLUOROTRYPTOPHAN;DL-2-AMINO-3-(5-FLUOROINDOLYL)PROPIONIC ACID;2-AMINO-3-(5-FLUORO-1H-INDOL-3-YL)PROPANOIC ACID
CAS:154-08-5
MF:C11H11FN2O2
MW:222.22
EINECS:205-822-5
Product Categories:Indoles and derivatives;Amino Acids 13C, 2H, 15N;Amino Acids & Derivatives;FA - FLPeptide Synthesis;Alphabetic;F;A - HPeptide Synthesis;Amino Acids;Modified Amino Acids;Tryptophan Derivatives;Unnatural Amino Acid Derivatives
Mol File:154-08-5.mol
5-FLUORO-DL-TRYPTOPHAN Chemical Properties
Melting point 265 °C (dec.)(lit.)
Boiling point 450.7±45.0 °C(Predicted)
density 1.2556 (estimate)
storage temp. Keep in dark place,Inert atmosphere,2-8°C
form powder
pka2.21±0.10(Predicted)
color white
BRN 22753
InChIKeyINPQIVHQSQUEAJ-UHFFFAOYSA-N
CAS DataBase Reference154-08-5(CAS DataBase Reference)
Safety Information
Hazard Codes Xi
Risk Statements 36/38
Safety Statements 22-24/25
WGK Germany 3
RTECS YN6825000
Hazard Note Irritant
HS Code 29339900
MSDS Information
ProviderLanguage
SigmaAldrich English
ACROS English
5-FLUORO-DL-TRYPTOPHAN Usage And Synthesis
Chemical Propertieslight beige powder
UsesA metabolic antagonist of tryptophan
DefinitionChEBI: A non-proteinogenic alpha-amino acid that is tryptophan in which the hydrogen at position 5 on the indole ring is replaced by a fluoro group.
Purification MethodsRecrystallise it from EtOH, aqueous EtOH or AcOH. Also purify it by passage through a Dowex AG1x2 (acetate form) column and recrystallise the L-enantiomer (from enzymic enrichment) from H2O/EtOH, m 158-163o(dec), [] D -8.3o (c 2.5, N NaOH). [Coy et al. Biochemistry 13 3550 1974, Beilstein 22/14 V 116.]

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