Wikstrol B (compound 5) is a biflavonoid microtubule / tubulin inhibitor and HIV-1 inhibitor. Wikstrol B has an IC 50 value of 184 μM for microtubule polymerization and an EC 50 of 3.02 μM against HIV-1 , acting on early events of HIV-1 replication. Wikstrol B exerts antifungal activity by inducing morphological deformation of Pyricularia oryzae hyphae and exerts anti-mitotic activity by inhibiting microtubule polymerization. Wikstrol B can be used in research related to antifungal , antitumor, and anti-AIDS applications. Wikstrol B can be naturally extracted from the roots of Wikstroemia indica .
Products | Products > Disease Areas > Infection | Products > Disease Areas > HIV Infection | Products > Disease Areas > Fungal Infection | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > Microtubule/Tubulin | Products > Signaling Pathways > HIV
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