Gymnoside II is one of the main bioactive constituents isolated from Bletilla striata. Gymnoside II inhibits nano SiO 2 -induced A549 cell viability reduction, apoptosis , and ROS generation by activating Nrf2 . Gymnoside II upregulates HO-1 and γ-GCSc , while downregulating the Bax/Bcl-2 ratio. Gymnoside II is applicable for research on nano SiO 2 -induced pulmonary injury.
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Respiratory Inflammation | Products > Disease Areas > Acute Lung Injury | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Bcl-2 Family | Products > Signaling Pathways > Keap1-Nrf2 | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Heme Oxygenase (HO)
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