Product

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one

CAS No.：1469337-95-8

Other grades of this product :

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Basic information

Product Name:	1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one
Synonyms:	1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one;2-Propen-1-one, 1-[4-[2-[(4-chloro-2-hydroxy-5-iodophenyl)aMino]acetyl]-1-piperazinyl]-;K-Ras G12C-IN-12;105456;CS-1676;G12C INHIBITOR 12;K RAS INHIBITOR 12;K RAS INHIBITOR 12; G12C INHIBITOR 12
CAS:	1469337-95-8
MF:	C15H17ClIN3O3
MW:	449.67
EINECS:
Product Categories:	Inhibitors
Mol File:	1469337-95-8.mol

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Chemical Properties

Boiling point	680.2±55.0 °C(Predicted)
density	1.736±0.06 g/cm3(Predicted)
solubility	≥8.98 mg/mL in DMSO with gentle warming
form	solid
pka	8.60±0.50(Predicted)

Safety Information

MSDS Information

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Usage And Synthesis

references

[1]. ostrem jm1, peters u, sos ml, et al. k-ras(g12c) inhibitors allosterically control gtp affinity and effector interactions. nature, 2013, 503(7477): 548-551.

1-(4-(2-((4-chloro-2-hydroxy-5-iodophenyl)aMino)acetyl)piperazin-1-yl)prop-2-en-1-one Preparation Products And Raw materials

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