Other grades of this product :
| 13,14-Didehydromatridin-15-one Basic information |
| Product Name: | 13,14-Didehydromatridin-15-one | | Synonyms: | SOPHOCARPINE;13,14-didehydromatridin-15-one;(6AS,11AR,11BR,11CS)-2,3,5,6,6A,7,11,11A,11B,11C-DECAHYDRO-1H,4H-3A,7A-DIAZA-BENZO[DE]ANTHRACEN-8-ONE;Matridine-13-ene-15-one;(41S,7aS,13aR,13bR)-2,3,41,6,7,7a,8,13,13a,13b-Decahydro-1H,5H,10H-dipyrido[2,1-f:3',2',1'-ij][1,6]naphthyridin-10-one hydrate;Sophocarpine Monohydrate;Sophocarpinpe;Sophora alkaloids | | CAS: | 145572-44-7 | | MF: | C15H22N2O | | MW: | 246.35 | | EINECS: | | Product Categories: | Inhibitors;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract | | Mol File: | 145572-44-7.mol |
| 13,14-Didehydromatridin-15-one Chemical Properties |
| Melting point | 8l-2°C | | storage temp. | -20°C Freezer | | solubility | Acetone; Dichloromethane | | form | Solid | | color | Pale brownish |
| 13,14-Didehydromatridin-15-one Usage And Synthesis |
| Description | A tetracyclic alkaloid present in Sophora species, this base crystallizes from H20
as the monohydrate, m.p. 54-5°C which becomes anhydrous in vacuo. It has
[α]18D - 29.44° (EtOH) and yields the following salts: hydrochloride, m.p. >
300°C; hydriodide, m.p. 277-9°C; aurichloride, m.p. l66-7°C; platinichloride,
m.p. 207-212°C (dec.); picrate, m.p. ISS-7°C and the methiodide, m.p. 200-2°C. Reduction of the base by electrolysis yields a crystalline, volatile base,
ClsH26N2, b.p. l53-4°C/5 mm; [α]D - 26.2° (EtOH) and giving a methiodide
with a melting point above 300°C. Attempted degradation by the Hofmann
process has proved unsuccessful. | | Uses | Sophocarpine Monohydrate alleviates non-alcoholic steatohepatitis, which is a resultant effect of non-alcoholic fatty lifer disease. Admission of this compound results in a decrease in liver weight and serum lipids. Antiviral agent, Sophocarpine also displays a profound effect against coxsackievirus and therapeutical effects of viral myocarditis. | | References | Orekhov, Proskurnina., Ber., 67,77 (1934)
Proskurnina, Kuzuvkov., Dokl. Akad. Nauk SSSR, 91, 1145 (1953)
Okuda et al., Chern. & Ind., 1326 (1962) |
| 13,14-Didehydromatridin-15-one Preparation Products And Raw materials |
|
日本语
한국어
Français
Deutsch
España
Türkiye