Brutieridin (Compound 1) is a flavanone glycoside that can be isolated from the juice of bergamot ( Citrus bergamia ). Brutieridin reduces the level of NPC1L1 in intestinal epithelial cells. Brutieridin decreases cholesterol uptake by intestinal epithelial cells. Brutieridin reduces HMGR activity. Brutieridin can be used in the research of hypercholesterolemia.
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