Caudatin (Standard)

Overview

Caudatin (Standard) is the analytical standard of Caudatin ( HY-N1983 ). This product is intended for research and analytical applications. Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis , autophagy , ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP , caspase-3 , -7 , -9 , upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL . Caudatin suppresses VEGF , FAK phosphorylation, upregulates p21 , p27 , DR 5 protein expression, activates the p38 MAPK , JNK and PPARα/TFEB -mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer , inflammation and neurological disease , such as glioma and Alzheimer's disease.

Application

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Product Information

• Catalog No.: HY-N1983R
• CAS No.: 38395-02-7
• Molecular Formula: C28H42O7
• Molecular Weight: 490.63
• Purity: 99.31%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source