Tubulysin D

Overview

Tubulysin D is a highly cytotoxic anti-microtubule toxin ( anti-microtubule toxins ) that is synthesized as an ADC cytotoxin ( ADC Cytotoxin ). Tubulysin D can be isolated from the myxobacteria Archangium geophyra and Angiococcus disciformis . Tubulysin D displays extremely potent cytotoxic activity in mammalian cells, including multidrug-resistant cell lines, with IC 50 values in the low nanomolar range. Tubulysin D inhibits microtubule/Tubulin polymerization and leads to cell cycle arrest and apoptosis .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Antibody-Drug Conjugate/ADC Related | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > ADC Payloads | Products > Signaling Pathways > Microtubule/Tubulin

Product Information

• Catalog No.: HY-N2348
• CAS No.: 309935-57-7
• Molecular Formula: C43H65N5O9S
• Molecular Weight: 828.07
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source