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| SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA Basic information |
| SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA Chemical Properties |
| storage temp. | −20°C | | solubility | 0.1 M acetic acid: soluble1mg/mL | | form | powder | | color | white | | BRN | 5153552 |
| SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA Usage And Synthesis |
| Uses | Substance P acetate salt hydrate has been:- used as a neurokinin 1 (NK1) receptor agonist for the activation of spinal nociceptive circuitry in mice
- administered in central nucleus (ACE) in rat to study its positive reinforcing effects
- used as an inhibitor of myosin light chain kinase in isolated lymphatic vessels from rat
| | General Description | Substance P is a small peptide produced by macrophages, lymphocytes, eosinophils, dendritic cells and nerves. It is part of the neurokinin group. | | Biochem/physiol Actions | NK-1 agonist; potent vasodilator and hypotensive agent; induces salivation; increases capillary permeability; induces mast cell degranulation; putative neurotransmitter in sensory (pain) afferents. |
| SUBSTANCE P ACETATE SALT HYDRATE, BIOCHEMIKA Preparation Products And Raw materials |
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