Hirsutanonol ((5S)-Hirsutanonol) is a diarylheptanoid that can be isolated from the bark of Alnus hirsute var. sibirica. Hirsutanonol inhibits cyclooxygenase-2 ( COX-2 ) expression. Hirsutanonol has anti-filarial with an IC 50 value of 44.11 μg/mL for microfilariae.
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