Cephaeline

Overview

Cephaeline ((-)-Cephaeline), a desmethyl analog of Emetine, is a phenolic alkaloid in Indian Ipecac roots isolated from the Cephaelis ipecacuanha. Cephaeline exhibits potent inhibition of both Zika virus ( ZIKV ) and Ebola virus ( EBOV ) infections. Cephaeline is an inductor of histone H3 acetylation and an inhibitor of mucoepidermoid carcinoma cancer stem cells ( MEC ), which promotes ferroptosis by inhibiting NRF2 to exert anti-lung cancer efficacy.

Application

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Product Information

• Catalog No.: HY-N4118
• CAS No.: 483-17-0
• Molecular Formula: C28H38N2O4
• Molecular Weight: 466.61
• Purity: 99.77%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (5.36 mM); Clear solution
• Availability: In-stock

Source

Original product source