Oxyberberine

Overview

Oxyberberine (Oxyberberin; Berlambine) is an orally effective heme oxygenase HO-1 agonist that can activate antioxidant mechanisms by regulating the PI3K/Akt/AMPK signaling pathway. Oxyberberine induces HO-1 expression, increases SOD and GSH-Px activity, inhibits NF-κB-mediated inflammatory responses, and improves insulin sensitivity and glucose metabolism. Oxyberberine has anti-diabetic, neuroprotective, anti-inflammatory and antioxidant effects, and can be used to study type 2 diabetes, traumatic brain injury (TBI) and inflammatory bowel disease.

Application

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Product Information

• Catalog No.: HY-N5027
• CAS No.: 549-21-3
• Molecular Formula: C20H17NO5
• Molecular Weight: 351.35
• Purity: 99.78%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1.67 mg/mL (4.75 mM); Clear solution
• Availability: In-stock

Source

Original product source