Other grades of this product :
| Product Name: | ML167 | | Synonyms: | ML167;ML167/ML-167;5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol;CID 44968231;5-[4-[[(5-Methyl-2-furanyl)methyl]amino]-6-quinazolinyl]-2-furanmethanol ML167;NCGC00188654;(5-(4-(((5-Methylfuran-2-yl)methyl)amino)quinazolin-6-yl)furan-2-yl)methanol;CID44968231;NCGC00188654 | | CAS: | 1285702-20-6 | | MF: | C19H17N3O3 | | MW: | 335.36 | | EINECS: | 808-432-9 | | Product Categories: | Inhibitors | | Mol File: | 1285702-20-6.mol |
| ML167 Chemical Properties |
| storage temp. | -20°C | | solubility | DMSO: soluble10mg/mL, clear | | form | powder | | color | off-white to gray to brown | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 3 months. |
| Hazard Codes | Xn | | Risk Statements | 22 | | Safety Statements | 46 | | WGK Germany | 3 |
| ML167 Usage And Synthesis |
| Description | ML167 (1285702-20-6) is a highly selective cell permeable inhibitor of Cdc2-like kinase 4 (Clk4) – IC50?= 136nM. It displays at least 10-fold greater selectivity over the related kinases Clk1(1.52 μM), Clk2(1.65μM), Clk3(>10μM), Dyrk1A(>10μM), and Dyrk1B(4.4 μM). | | References | 1) Rosenthal?et al. (2010),?An inhibitor of the Cdc2-like kinase 4 (Clk4); Probe Reports from the NIH Molecular Libraries Program |
| ML167 Preparation Products And Raw materials |
|