Aselacin A targets endothelin-1 receptor ( ET-1 receptor ), inhibits the the binding of ET-1 to ETA receptor and ETB receptor . Aselacin A inhibits the ET-1 binding to bovine atrial membrane and porcine cerebral membrane with IC 50 of 22 μg/mL and 20 μg/mL. Aselacin A can be used for research of cardiovascular diseases.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Endothelin Receptor
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