Leptomycin A

Overview

Leptomycin A, a Streptomyces metabolite, is an inhibitor of CRM1 (exportin 1) that blocks CRM1 interaction with nuclear export signals, preventing the nuclear export of a broad range of proteins. Leptomycin A suppresses HIV-1 replication. Less potent than Leptomycin B.

Application

Products | Products > Disease Areas > Infection | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Anti-infection | Products > Research Areas > Infection | Products > Signaling Pathways > CRM1 | Products > Signaling Pathways > HIV | Products > Signaling Pathways > Antibiotic

Product Information

• Catalog No.: HY-N6795
• CAS No.: 87081-36-5
• Molecular Formula: C32H46O6
• Molecular Weight: 526.70
• Purity: 99.98%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source