Other grades of this product :
| Product Name: | XL-388 | | Synonyms: | Methanone, [7-(6-amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-;[7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone XL388;XL388, >=98%;(7-(6-Aminopyridin-3-yl)-2,3-dihydrobenzo[f][1,4]oxazepin-4(5H)-yl)(3-fluoro-2-methyl-4-(methy;XL 388;XL388;XL-388;[7-(6-Amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone | | CAS: | 1251156-08-7 | | MF: | C23H22FN3O4S | | MW: | 455.5 | | EINECS: | | Product Categories: | PI3K/Akt/mTOR;Akt;Inhibitors;mTOR;PI3K | | Mol File: | 1251156-08-7.mol |
| XL-388 Chemical Properties |
| Melting point | >188oC (dec.) | | Boiling point | 738.6±60.0 °C(Predicted) | | density | 1.354±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Inert atmosphere,Store in freezer, under -20°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 6.22±0.13(Predicted) | | form | Solid | | color | Off-White to Pale Yellow | | Stability: | Hygroscopic |
| XL-388 Usage And Synthesis |
| Uses | XL388 is a highly potent, orally bioavailable, selective, ATP-competitive mammalian target of rapamycin (mTOR) inhibitor. XL388 has shown significant and dose-dependent antitumor activity in athymic nude mice implanted with human tumor xenografts. |
| XL-388 Preparation Products And Raw materials |
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