Phaseoloidin

Overview

Phaseoloidin is an orally active multi-target inhibitor. Phaseoloidin inhibits the activation of the NLRP3 inflammasome and blocks the caspase-11-GSDMD pyroptosis axis. Phaseoloidin reduces the expression of collagen-degrading enzymes to maintain the integrity of cartilage matrix. Phaseoloidin activates the AMPK / mTOR pathway to enhance autophagy function and reverse apoptosis resistance. Phaseoloidin inhibits the growth and development of Manduca sexta and Spodoptera littoralis larvae, thereby helping Nicotiana attenuata defend against lepidopteran herbivorous insects. Phaseoloidin can be used in research related to acute gouty arthritis and pulmonary fibrosis.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Others | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > AMPK | Products > Signaling Pathways > mTOR | Products > Signaling Pathways > Insecticide | Products > Signaling Pathways > NOD-like Receptor (NLR) | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-N7400
• CAS No.: 118555-82-1
• Molecular Formula: C14H18O9
• Molecular Weight: 330.29
• Purity: 99.92%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (7.57 mM); Clear solution
• Availability: In-stock

Source

Original product source