Narchinol B (Compound 4) is a sesquiter penoid compound. Narchinol B has anti-inflammatory effects. Narchinol B works by inhibiting proinflammatory mediators, including prostaglandin E2 (PGE2), inducible nitric oxide synthase ( iNOS ), and cyclooxygenase-2 ( COX-2 ) proteins, as well as proinflammatory cytokines, such as interleukin-1b, IL-6 , and tumor necrosis factor-α (TNF-α). Narchinol B significantly inhibits LPS-induced overproduction of NO in BV2 cells (IC 50 =2.43 μM) .
Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Research Areas > Inflammation/Immunology
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