AIP-II is a cyclic peptide signaling molecule for quorum sensing, which is produced by Staphylococcus aureus . AIP-II potently inhibits AgrC-III in Methicillin ( HY-121544 )-resistant type III Staphylococcus aureus strain AH1747, with an IC50 of 0.532 nM. AIP-II binds to the AgrC-II receptor and regulates virulence gene expression in Staphylococcus aureus .
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