Unlabeled FXX489 (NNS309) is a fibroblast activation protein ( FAP ) -targeting ligand. Unlabeled FXX489 can be labeled with 68 Ga and 177 Lu and shows anticancer effects. Unlabeled FXX489 can be used for the study of pancreatic ductal adenocarcinoma (PDAC), non-small cell lung cancer (NSCLC), breast cancer (BC), and colorectal cancer (CRC).
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