Ac-RHKK(Ac)-AMC (Compound S1) is a fluorescent substrate for SITR6 , that is based on p53 sequence. Ac-RHKK(Ac)-AMC mimics H3K56 deacetylation site and significantly increases the deacetylation signal with low signal-to-background ratio. Ac-RHKK(Ac)-AMC can be used for ageing and cancers research.
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