Urotensin I (Catostomus urotensin I), a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC 50 s of 11.46, 9.36 and 9.85 for human CRF 1 , human CRF 2 and rat CRF 2α receptors in CHO cells, and K i s of 0.4, 1.8, and 5.7 nM for hCRF 1 , rCRF 2α and mCRF 2β receptors, respectively.
Products | Products > Peptides | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Endocrinology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > CRFR
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