Product

DL-3-Aminoisobutyric acid

CAS No.：10569-72-9

Other grades of this product :

DL-3-Aminoisobutyric acid Basic information

Product Name:	DL-3-Aminoisobutyric acid
Synonyms:	DL-2-AMINO-ISO-BUTYRIC ACID;DL-3-AMINO-2-METHYLPROPIONIC ACID;DL-B-AMINOISOBUTYRIC ACID;H-AIB-OH;H-ALA(ME)-OH;H-ALPHA-METHYLALANINE;H-2-AMINOISOBUTYRIC ACID;H-(ME)ALA-OH
CAS:	10569-72-9
MF:	C4H9NO2
MW:	103.12
EINECS:	234-154-7
Product Categories:	Amino Acids;Amino Acids
Mol File:	10569-72-9.mol

DL-3-Aminoisobutyric acid Chemical Properties

Melting point	179-182 °C(lit.)
density	1.2300 (estimate)
refractive index	1.4650 (estimate)
storage temp.	-20°C
solubility	Methanol (Slightly), Water (Slightly)
form	Solid
color	White to Off-White
CAS DataBase Reference	10569-72-9(CAS DataBase Reference)
NIST Chemistry Reference	DL-Beta-aminoisobutyric acid(10569-72-9)

Safety Information

Safety Statements	22-24/25
WGK Germany	3
RTECS	AY7000000

MSDS Information

Provider	Language
DL-3-Amino-2-methylpropionic acid	English
ACROS	English
SigmaAldrich	English
ALFA	English

DL-3-Aminoisobutyric acid Usage And Synthesis

Uses

DL-3-Aminoisobutyric Acid is a useful compound for suppressing atherosclerosis in apolipoprotein E-knockout mouse.

Purification Methods

RS-β-Aminoisobutyric acid forms colourless prisms by crystallisation from hot H2O which are powdered and dried in vacuo. The purity is checked by paper chromatography (Whatman 1) using ninhydrin spray to visualise the amino acid; RF values in 95% MeOH and n-PrOH/5N HCOOH (8:2) are 0.36 and 0.50 respectively. [Kupiecki & Coon Biochemical Preparations 7 20 1960, Pollack J Am Chem Soc 65 1335 1943.] The R-enantiomer, isolated from iris bulbs or human urine, crystallises from H2O and sublimes in vacuo [Asen et al. J Biol Chem 234 343 1959]. The RS-hydrochloride crystallises from EtOH/Et2O with m 128-129o (also 130o) [B.hme et al. Chem Ber 92 1258, 1260, 1261 1959]. [Beilstein 4 III 1330.]

DL-3-Aminoisobutyric acid Preparation Products And Raw materials

Raw materials	3-[Bis(trimethylsilyl)amino]-2-methylpropanoic acid trimethylsilyl ester-->5-Isoxazolidinone, 4-methyl-2-(phenylmethyl)--->DIHYDROTHYMINE
Preparation Products	3-amino-2-methylpropan-1-ol-->R-b-aminoisobutyric acid-->Methyl 3-amino-2-methylpropanoate HCl

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