Nocistatin, a neuropeptide, is an endogenous ligand for the orphan opioid receptor-like receptor . Nocistatin is also a functional antagonist of neuropeptide nociceptin or orphanin FQ (Noc/OFQ). Nocistatin inhibits 5-HT release via a G i/o proteinmediated pathway. Nocistatin blocks Nociceptin ( Nociceptin )-induced allodynia and hyperalgesia.
Products | Products > Peptides | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Opioid Receptor
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