Other grades of this product :
| Product Name: | VX-222 | | Synonyms: | VX-222;5-(3,3-Dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]-2-thiophenecarboxylic acid;VCH 222;VCH222;VCH-222;VX-222, VCH222;VX-222 (VCH-222, LoMibuvir);2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[(cis-4-hydroxycyclohexyl)[(trans-4-methylcyclohexyl)carbonyl]amino]- | | CAS: | 1026785-59-0 | | MF: | C25H35NO4S | | MW: | 445.61 | | EINECS: | | Product Categories: | Inhibitors;Inhibitor | | Mol File: | 1026785-59-0.mol |
| VX-222 Chemical Properties |
| Boiling point | 640.5±55.0 °C(Predicted) | | density | 1.21 | | solubility | ≥44.6 mg/mL in DMSO; insoluble in H2O; ≥97.2 mg/mL in EtOH | | form | solid | | pka | 3.67±0.10(Predicted) |
| VX-222 Usage And Synthesis |
| Description | Lomibuvir is a non-nucleoside inhibitor of the RNA-directed RNA polymerase of hepatitis C virus (HCV; Ki = 17 nM) that inhibits primer-dependent RNA synthesis selectively over de novo RNA synthesis. It inhibits HCV replication in Huh7.5 cells expressing the 1b/Con1 HCV subgenomic replicon (EC50 = 5 nM). | | Uses | VX-222, s a novel, potent and selective inhibitor of HCV polymerase . |
| VX-222 Preparation Products And Raw materials |
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