L-Histidine hydrochloride

L-Histidine hydrochloride
  • CAS No.:1007-42-7
Other grades of this product :
L-Histidine hydrochloride Basic information
Product Name:L-Histidine hydrochloride
Synonyms:H-His-OH.xHCl;L-HISTIDINE DIHYDROCHLORIDE;Crystalline2HCl;L-Histidine hydrochloride;L-Histidine hydrochloride solution;histidine hydrochloride;China Best L-Histidine hydrochloride CAS NO.1007-42-7;L-Histidine hydrochloride CAS NO.1007-42-7
CAS:1007-42-7
MF:C6H10ClN3O2
MW:191.62
EINECS:213-754-2
Product Categories:
Mol File:1007-42-7.mol
L-Histidine hydrochloride Chemical Properties
Melting point 240-245 °C (dec.)
alpha [α]D20 +7.0~+10.0°(c=2,HCl)
storage temp. Inert atmosphere,Room Temperature
CAS DataBase Reference1007-42-7(CAS DataBase Reference)
Safety Information
Safety Statements 22-24/25
RIDADR UN 1789 8/PG 3
WGK Germany 3
3-10
MSDS Information
ProviderLanguage
SigmaAldrich English
L-Histidine hydrochloride Usage And Synthesis
Purification MethodsThe dihydrochloride crystallises from water or aqueous EtOH and is washed with acetone, then diethyl ether. Alternatively convert it to the histidine di-(3,4-dichlorobenzenesulfonate) salt by dissolving 3,4-dichlorobenzenesulfonic acid (1.5g/10mL) in the aqueous histidine solution with warming, and then the solution is cooled in ice. The resulting crystals (m 280o dec) can be recrystallised from 5% aqueous 3,4-dichlorobenzenesulfonic acid, then dried over CaCl2 under vacuum, and washed with diethyl ether to remove Purification of Biochemicals — Amino Acids and Peptides excess reagent. The dihydrochloride can be regenerated by passing the solution through a Dowex-1 (Cl-form) ion-exchange column. The solid is obtained by evaporation of the solution on a steam bath or better in a vacuum. [Greenstein & Winitz, The Amino Acids Vol 3 p 1976 1961, Beilstein 25/16 V 366.]
L-Histidine hydrochloride Preparation Products And Raw materials
Raw materialsHEMOGLOBIN
Preparation ProductsN-Boc-L-Histidine

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