2,5-Dichloronitrobenzene

CAS No.：89-61-2

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2,5-Dichloronitrobenzene Basic information

Product Name:	2,5-Dichloronitrobenzene
Synonyms:	Benzene, 2,5-dichloronitro-;Benzene,1,4-dichloro-2-nitro-;Benzene,1-nitro-2,5-dichloro;NITRO-P-DICHLOROBENZENE;2-NITRO-1,4-DICHLOROBENZENE;2-NITRO-P-DICHLOROBENZENE;2,5-DICHLORO-1-NITROBENZENE;2,5-DICHLORONITROBENZENE
CAS:	89-61-2
MF:	C6H3Cl2NO2
MW:	192
EINECS:	201-923-3
Product Categories:	Aromatic Halides (substituted);Benzene derivates;Intermediates of Dyes and Pigments;Dyestuff Intermediates
Mol File:	89-61-2.mol

2,5-Dichloronitrobenzene Chemical Properties

Melting point	52-54 °C(lit.)
Boiling point	267 °C
density	1,442 g/cm³
vapor density	6.6 (vs air)
vapor pressure	<0.1 mm Hg ( 25 °C)
refractive index	1.4390 (estimate)
Fp	>230 °F
storage temp.	Store below +30°C.
solubility	0.083g/l
form	neat
color	Pale Yellow
explosive limit	2.4-8.5%(V)
Water Solubility	Soluble in water, ethanol, ether, benzene, carbon disulfide. Slightly soluble in carbon tetrachloride.
BRN	778109
LogP	2.87 at 25℃
CAS DataBase Reference	89-61-2(CAS DataBase Reference)
IARC	2B (Vol. 65, 123) 2020
NIST Chemistry Reference	Benzene, 1,4-dichloro-2-nitro-(89-61-2)
EPA Substance Registry System	2,5-Dichloronitrobenzene (89-61-2)

Safety Information

Hazard Codes	Xn,N
Risk Statements	22-36-51/53
Safety Statements	26-60
RIDADR	UN 3077 9/PG 3
WGK Germany	2
RTECS	CZ5260000
TSCA	Yes
HazardClass	9
PackingGroup	III
HS Code	29049085
Hazardous Substances Data	89-61-2(Hazardous Substances Data)

MSDS Information

Provider	Language
Nitro-p-dichlorobenzene	English
SigmaAldrich	English
ACROS	English
ALFA	English

2,5-Dichloronitrobenzene Usage And Synthesis

Chemical Properties	yellow flakes
Uses	2,5-Dichloronitrobenzene is a reagent used in the synthesis of antitrypanosomal, antileishmanial and antimalarial agents. Also it is used in the synthesis of lysophosphatidic acid acyltransferase-β in hibitors.
Uses	2,5-Dichloronitrobenzene is a reagent used in the synthesis of antitrypanosomal, antileishmanial and antimalarial agents. Also it is used in the synthesis of lysophosphatidic acid acyltransferase-β inhibitors.
Purification Methods	Crystallise the nitrobenzene from absolute EtOH. [Beilstein 5 IV 726.]

2,5-Dichloronitrobenzene Preparation Products And Raw materials

Raw materials

Sulfuric acid-->Nitric acid-->Water-->p-Dichlorobenzene-->1,4-Dichlorobenzene-->Benzaldehyde, 3,6-dichloro-2-nitro--->3,4-DINITROANILINE-->1-(4-chloro-2-nitrophenyl)ethanone-->3-CHLORO-4-NITROANILINE-->4-Chloro-2-nitrobenzoic acid

Preparation Products

2,5-Dichloroaniline-->6-Chlorooxindole-->Clozapine-->4-Chloro-2-nitroaniline-->N-(2-AMINO-4-CHLOROPHENYL)ANTHRANILIC ACID-->4-CHLORO-2-NITROPHENOL-->2,5-Dichlorophenylhydrazine hydrochloride-->4-Chloro-2-nitrotoluene-->2-AMINO-4,4'-DICHLORODIPHENYL ETHER-->5-Chloro-2-methoxyaniline-->5-Chloro-2-phenoxyaniline-->Azoic Diazo Component 33-->4-Chloro-N-(4-methoxyphenyl)-2-nitroaniline-->4-chloro-2-nitro-N-phenylaniline

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