TGN-020

Overview

TGN-020 is a selective Aquaporin 4 (AQP4) inhibitor with an IC 50 of 3.1 μM. TGN-020 is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs .TGN-020 alleviates edema and inhibits glial scar formation after spinal cord compression injury in rats.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > PROTAC | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTAC Linkers

Product Information

• Catalog No.: HY-W008574
• CAS No.: 51987-99-6
• Molecular Formula: C8H6N4OS
• Molecular Weight: 206.23
• Purity: 99.97%
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 1.67 mg/mL (8.10 mM); Clear solution
• Availability: In-stock

Source

Original product source