Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H + , K + -ATPase . Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H + , K + -ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease.
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