N-Fmoc-8-aminooctanoic acid

Overview

N-Fmoc-8-aminooctanoic acid can be used as a PROTAC linker in the synthesis of PROTACs . N-Fmoc-8-aminooctanoic acid is an alkane chain with terminal Fmoc-protected amine and carboxylic acid groups. The Fmoc group can be deprotected under basic condition to obtain the free amine which can be used for further conjugations. The terminal carboxylic acid can react with primary amine groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PROTAC | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PROTAC Linkers

Product Information

• Catalog No.: HY-W009030
• CAS No.: 126631-93-4
• Molecular Formula: C23H27NO4
• Molecular Weight: 381.46
• Purity: 98.95%
• Storage: Store at room temperature 3 years. In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source