Win 18446 is an orally active testes-specific enzyme ALDH1a2 inhibitor, with an IC50 of 0.3 μM. Win 18446 reversibly inhibits spermatogenesis in many species and inhibits Retinoic acid ( HY-14649 ) biosynthesis from Retinol ( HY-B1342 ) within the testes.
Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > Others | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Reference Standards | Products > Signaling Pathways > Aldehyde Dehydrogenase (ALDH)
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