4-Methyl-2-oxopentanoic acid -d 7 (α-Ketoisocaproic acid-d 7 ) sodium is the deuterium labeled 4-Methyl-2-oxopentanoic acid ( HY-W012722 ).4-Methyl-2-oxopentanoic acid is a metabolite of L-leucine and is involved in energy metabolism. 4-Methyl-2-oxopentanoic acid increases endoplasmic reticulum stress, promotes lipid accumulation in preadipocytes and insulin resistance by impairing mTOR and autophagy signaling pathways.
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